Invitrogen™ SPOCK1 Monoclonal Antibody (316801)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524039

Catalog No. PIMA524039

Description

In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) Testican 2 or rhTestican 3 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

SPOCK1, also known as Testican-1, is a gene located on chromosome 5q31.2, encoding a member of the proteoglycan family characterized by containing multiple domains that facilitate interactions with other extracellular matrix proteins. SPOCK1 is primarily expressed in various tissues, including the brain and reproductive organs, where it plays crucial roles in modulating cell adhesion, migration, and matrix remodeling. Functionally, SPOCK1 contributes to the regulation of extracellular matrix composition, influencing processes such as tissue development and wound healing. In the context of cancer, SPOCK1 is often upregulated, promoting tumor progression and metastasis by enhancing cancer cell motility and invasiveness. Its involvement in these pathological mechanisms makes SPOCK1 a potential biomarker for cancer prognosis and a target for therapeutic intervention. Research continues to unravel SPOCK1's diverse biological activities and its impact on cellular architecture and disease progression.

Specifications

• Antigen: SPOCK1
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q08629
• Gene Symbols: SPOCK1
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Testican 1/SPOCK1 Arg22-Trp439.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunoprecipitation, Western Blot
• Clone: 316801
• Conjugate: Unconjugated
• Gene: SPOCK1
• Gene Alias: FLJ37170; Protein SPOCK; sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1; sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1; Spock; Spock1; testican; testican 1; testican-1; TIC1; TICN1
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 6695
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized