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Invitrogen™ SPOCK1 Polyclonal Antibody
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Catalog No. PIPA548008
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100 μg
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PIPA548008 100 μg
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Catalog No. PIPA548008 Supplier Invitrogen™ Supplier No. PA548008
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Description

Goat Polyclonal Antibody

In Western blots, approximately 10% cross-reactivity with recombinant human (rh) Testican 2 is observed and less than 2% cross-reactivity with rhTestican 3 is observed. Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

SPOCK1, also known as Testican-1, is a gene located on chromosome 5q31.2, encoding a member of the proteoglycan family characterized by containing multiple domains that facilitate interactions with other extracellular matrix proteins. SPOCK1 is primarily expressed in various tissues, including the brain and reproductive organs, where it plays crucial roles in modulating cell adhesion, migration, and matrix remodeling. Functionally, SPOCK1 contributes to the regulation of extracellular matrix composition, influencing processes such as tissue development and wound healing. In the context of cancer, SPOCK1 is often upregulated, promoting tumor progression and metastasis by enhancing cancer cell motility and invasiveness. Its involvement in these pathological mechanisms makes SPOCK1 a potential biomarker for cancer prognosis and a target for therapeutic intervention. Research continues to unravel SPOCK1's diverse biological activities and its impact on cellular architecture and disease progression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SPOCK1
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene SPOCK1
Gene Accession No. Q08629
Gene Alias FLJ37170; Protein SPOCK; sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1; sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1; Spock; Spock1; testican; testican 1; testican-1; TIC1; TICN1
Gene Symbols SPOCK1
Host Species Goat
Immunogen Mouse myeloma cell line NS0-derived recombinant human Testican1/SPOCK1 Arg22-Trp439.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6695
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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