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Invitrogen™ SPP24 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA5122309
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100 μL
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PIPA5122309 20 μL
PIPA5122308 100 μL
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Catalog No. PIPA5122309 Supplier Invitrogen™ Supplier No. PA5122309
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Description

Rabbit Polyclonal Antibody

SPP24, also known as secreted phosphoprotein 2, is a 211 amino acid secreted protein that belongs to the cystatin superfamily. Expressed in liver and plasma, SPP24 may play a role in coordinating an aspect of bone turnover. The gene that encodes SPP24 maps to human chromosome 2, which consists of 237 million bases encoding over 1,400 genes, making up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SPP24
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene SPP2
Gene Accession No. Q13103
Gene Alias secreted phosphoprotein 2; secreted phosphoprotein 2, 24kD; secreted phosphoprotein 2, 24kDa; secreted phosphoprotein 24; SPP2; SPP24; SPP-24
Gene Symbols SPP2
Host Species Rabbit
Immunogen Phe30-Glu211 (Accession Q13103), with N-terminal His Tag.
Purification Method Antigen affinity chromatography, Protein A
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6694
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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