Invitrogen™ SPPL2A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA566909

Catalog No. PIPA566909

Description

Immunogen sequence: KFWKGNSYQMM DHLDCATNEE NPVISGEQIV QQ Highest antigen sequence identity to the following orthologs - mouse 79%, rat 73%.

By searching sequence databases for homologs of Dictyostelium discoideum Impas, which shares homology with presenilin, followed by PCR of lymphocyte and hippocampus cDNA libraries, Grigorenko et al. (2002) cloned SPPL2a. This protein, which may act as an intramembrane protease, contains an N-terminal protease-associated (PA) domain, several transmembrane regions, a hydrophilic loop, conservative sequences around the first and second aspartate residues, and an invariant PAL motif near the C terminus.

Specifications

• Antigen: SPPL2A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SPPL2A
• Gene Alias: 2010106G01Rik; C130089K23Rik; IMP3; IMP-3; intramembrane cleaving protease; intramembrane protease 3; MNCb-3763; Presenilin-like protein 2; protein SPPL2a; PSEC0147; PSL2; RGD1563001; signal peptide peptidase like 2A; signal peptide peptidase-like 2A; SPPL2A; SPPL2a protein; SPP-like 2A; SPP-like 2A protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84888
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8TCT8
• Gene Symbols: SPPL2A
• Immunogen: Recombinant Human SPPL2A. Recombinant protein control fragment (Product #RP-107561).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG