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Invitrogen™ SPPL2B Polyclonal Antibody
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Catalog No. PIPA565229
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100 μL
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PIPA565229 100 μL
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Catalog No. PIPA565229 Supplier Invitrogen™ Supplier No. PA565229
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: YWAGSRDVKKR YMKHKRDDGP EKQEDEAVDV Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 90%.

SPPL2B is a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SPPL2B
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SPPL2B
Gene Accession No. Q8TCT7
Gene Alias 3110056O03Rik; AW550292; IMP4; IMP-4; intramembrane protease 4; KIAA1532; MGC111084; Presenilin homologous protein 4; presenilin-like protein 1; protein SPPL2b; protein SPP-like 2B; PSH4; PSL1; RGD1308556; signal peptide peptidase like 2B; signal peptide peptidase-like 2B; SPPL2B; SPP-like 2B
Gene Symbols SPPL2B
Host Species Rabbit
Immunogen Recombinant Human SPPL2B. Recombinant protein control fragment (Product #RP-104701).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56928
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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