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Invitrogen™ SPRY2 Polyclonal Antibody
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Catalog No. PIPA543583
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100 μL
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PIPA543583 100 μL
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Catalog No. PIPA543583 Supplier Invitrogen™ Supplier No. PA543583
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Description

Rabbit Polyclonal Antibody

Peptide sequence: MEARAQSGNG SQPLLQTPRD GGRQRGEPDP RDALTQQVHV LSLDQIRAIR Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 92%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 86%; Rat: 100%.

This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SPRY2
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene SPRY2
Gene Accession No. O43597
Gene Alias hSPRY2; IGAN3; MGC23039; protein sprouty homolog 2; sprouty 2; sprouty homolog 2; sprouty homolog 2 (Drosophila); sprouty RTK signaling antagonist 2; sprouty2; SPRY2; spry-2
Gene Symbols SPRY2
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal of human SPRY2 (aa 1-50).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10253
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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