Invitrogen™ SPTY2D1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA565486

Catalog No. PIPA565486

Description

Immunogen sequence: SGPGRSISGSI PAGRTVSNSV PGRPVSSLGP GQTVSSSGPT IKPKCTVVSE TISSKNIISR SSNGQMNGMK PPLSGYRAAQ GPQRLPFPTG YKRQREYEE Highest antigen sequence identity to the following orthologs - mouse 86%, rat 83%.

Histone chaperone that stabilizes pre-existing histone tetramers and regulates replication-independent histone exchange on chromatin (PubMed:26109053). Required for normal chromatin refolding in the coding region of transcribed genes, and for the suppression of spurious transcription (PubMed:26109053). Binds DNA and histones and promotes nucleosome assembly (in vitro) (PubMed:23378026, PubMed:26109053). Facilitates formation of tetrameric histone complexes containing histone H3 and H4 (PubMed:26109053). Modulates RNA polymerase 1-mediated transcription. Binds DNA, with a preference for branched DNA species, such as Y-form DNA and Holliday junction DNA (PubMed:23378026).

Specifications

• Antigen: SPTY2D1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SPTY2D1
• Gene Alias: DKFZp686I068; FLJ39441; Protein KU002155; Protein SPT2 homolog; Spt2; SPT2 chromatin protein domain containing 1; SPT2 domain-containing protein 1; SPT2, Suppressor of Ty, domain containing 1; SPTY2D1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 144108
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q68D10
• Gene Symbols: SPTY2D1
• Immunogen: Recombinant Human SPTY2D1. Recombinant protein control fragment (Product #RP-104840).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG