Invitrogen™ SQLE Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA576523

Catalog No. PIPA576523

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

SQLE, also named as ERG1, SE and SM, belongs to the squalene monooxygenase family. It catalyzes the first oxygenation step in cholesterol synthesis, acting on squalene before cyclization into the basic steroid structure. SQLE may serve as a flux-controlling enzyme beyond 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR, considered as rate limiting). It is also post translationally regulated by cholesterol-dependent proteasomal degradation. The MW of SQLE is about 64 kDa.

Specifications

• Antigen: SQLE
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SQLE
• Gene Alias: AI323792; Erg1; FLJ30795; SE; Sqle; Squalene epoxidase; squalene monooxygenase; Squalene monooxygenase-like protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20775, 29230, 6713
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P52019, P52020, Q14534
• Gene Symbols: SQLE
• Immunogen: Recombinant fusion protein of human SQLE.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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