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Invitrogen™ SQLE Polyclonal Antibody
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Catalog No. PIPA596127
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100 μL
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PIPA596127 100 μL
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Catalog No. PIPA596127 Supplier Invitrogen™ Supplier No. PA596127
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Description

Rabbit Polyclonal Antibody

Positive Samples: SKOV3, Mouse liver, Mouse kidney, Rat liver; Cellular Location: Endoplasmic reticulum membrane, Microsome membrane, Multi-pass membrane protein Immunogen sequence: VSVSSHFVGF LMKNAPQFKA NHAELILANP SPVLIYQISS SETRVLVDIR GEMPRNLREY MVEKIYPQIP DHLKEPFLEA TDNSHLRSMP ASFLPPSSVK K.

SQLE, also named as ERG1, SE and SM, belongs to the squalene monooxygenase family. It catalyzes the first oxygenation step in cholesterol synthesis, acting on squalene before cyclization into the basic steroid structure. SQLE may serve as a flux-controlling enzyme beyond 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR, considered as rate limiting). It is also post translationally regulated by cholesterol-dependent proteasomal degradation. The MW of SQLE is about 64 kDa.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SQLE
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.7 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
Gene SQLE
Gene Accession No. P52019, P52020, Q14534
Gene Alias AI323792; Erg1; FLJ30795; SE; Sqle; Squalene epoxidase; squalene monooxygenase; Squalene monooxygenase-like protein
Gene Symbols SQLE
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20775, 29230, 6713
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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