Invitrogen™ SQSTM1 Monoclonal Antibody (GT381)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA531499

Catalog No. PIMA531499

Description

Keep as concentrated solution. Positive Control: HepG2, A549, H1299, Huh-7 (untreated), Huh-7 (3 μM Thapsigargin treatment for 12 hr), Huh-7 (3 μM Thapsigargin treatment for 24 hr). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Specifications

• Antigen: SQSTM1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: O08623, Q13501
• Gene Symbols: Sqstm1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human SQSTM1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot, Immunocytochemistry
• Clone: GT381
• Conjugate: Unconjugated
• Gene: Sqstm1
• Gene Alias: A170; EBI3-associated protein of 60 kDa; EBI3-associated protein p60; EBIAP; FTDALS3; hypothetical protein 1; ORCA; OSF-6; Osi; OSIL; oxidative stress induced; oxidative stress induced like; p60; p62; p62B; PDB3; phosphotyrosine independent ligand for the Lck SH2 domain p62; phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa; PKC-zeta-interacting protein; protein kinase C-zeta-interacting protein; sb:cb621; Sequestosome 1; sequestosome-1; Sqstm1; STAP; STONE14; ubiquitin-binding protein p62; Unknown (protein for MGC:127197); zgc:85784; ZIP; ZIP3
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 113894, 8878
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid