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Invitrogen™ SQSTM1 Polyclonal Antibody
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Catalog No. PIPA534781
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100 μL
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PIPA534781 100 μL
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Catalog No. PIPA534781 Supplier Invitrogen™ Supplier No. PA534781
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: Raji, K562, HL-60, NCI-H929, HepG2, HepG2 (3 μM Thapsigargin for 12 hr). Predicted reactivity: Mouse (88%), Rat (88%), Sheep (94%), Rhesus Monkey (98%), Bovine (93%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SQSTM1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Sqstm1
Gene Accession No. Q13501, Q64337
Gene Alias A170; EBI3-associated protein of 60 kDa; EBI3-associated protein p60; EBIAP; FTDALS3; hypothetical protein 1; ORCA; OSF-6; Osi; OSIL; oxidative stress induced; oxidative stress induced like; p60; p62; p62B; PDB3; phosphotyrosine independent ligand for the Lck SH2 domain p62; phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa; PKC-zeta-interacting protein; protein kinase C-zeta-interacting protein; sb:cb621; Sequestosome 1; sequestosome-1; Sqstm1; STAP; STONE14; ubiquitin-binding protein p62; Unknown (protein for MGC:127197); zgc:85784; ZIP; ZIP3
Gene Symbols Sqstm1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human SQSTM1/P62. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18412, 8878
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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