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Squalene Epoxidase Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501985985
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50-198-5985 100 μL
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Catalog No. 50-198-5985 Supplier Bioss Supplier No. BS4218R
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Rabbit Polyclonal Antibody

SQLE, also named as ERG1, SE and SM, belongs to the squalene monooxygenase family. It catalyzes the first oxygenation step in cholesterol synthesis, acting on squalene before cyclization into the basic steroid structure. SQLE may serve as a flux-controlling enzyme beyond 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR, considered as rate limiting). It is also post translationally regulated by cholesterol-dependent proteasomal degradation. The MW of SQLE is about 64 kDa.

Specifications

Antigen Squalene Epoxidase
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene SQLE
Gene Accession No. Q14534
Gene Alias AI323792; BOS_13796; Erg1; FLJ30795; LOC100356021; SE; SQLE; Squalene epoxidase; Squalene monooxygenase
Gene Symbols SQLE
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Squalene Epoxidase.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6713
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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