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  5. Tocris Bioscience™ SR 48692

Tocris Bioscience™ SR 48692
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Catalog No. 37215
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Quantity:
5 mg
25 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective non-peptide NTS1 antagonist

SR 48692 is a neurotensin antagonist; selective for NTS1 over NTS2 (apparent affinity, Ke, is 36 nM for NTS1). Competitively inhibits binding of [125I]-neurotensin to HT29 and N1E115 cell membranes (IC50 values are 15.3 and 20.4 nM respectively). Orally bioavailable.

Specifications

Chemical Name or Material 2-[[[1-(7-Chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]amino]-tricyclo[3.3.1.13,7]decane-2-carboxylic acid
CAS 146362-70-1
Assay Percent Range >98%
Quantity 5 mg
Molecular Formula C32H31ClN4O5
Formula Weight Observed MW: 587.07
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