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Invitrogen™ SRC3 Monoclonal Antibody (AX15.3)
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Catalog No. MA1845
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100 μg
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Catalog No. Quantity
MA1845 100 μg
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Catalog No. MA1845 Supplier Invitrogen™ Supplier No. MA1845
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Description

Mouse Monoclonal Antibody

MA1-845 detects amplified in breast cancer-1 (AIB1) in human cells. MA1-845 has been successfully used in Western blot and immunoprecipitation, ChIP, and immunohistochemistry procedures. By Western blot, this antibody detects an ~155 kDa protein representing AIB1 from MCF-7 cell extract. The MA1-845 immunizing peptide corresponds to amino acid residues 605-1294 of human AIB1.

AIB1-AC3 recognizes AIB1, a member of the SRC-1 family of nuclear receptor coactivators with an apparent molecular weight of 160kDa. The AIB1 gene has been mapped to region 20q12 and has been shown to be amplified in breast tumors and pancreatic cancer cell lines. AIB1 interacts in a ligand-dependent fashion with the estrogen receptor to enhance estrogen-dependent transcriptional gene activation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SRC3
Applications ChIP Assay, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone AX15.3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1 mg/mL BSA and 0.05% sodium azide
Gene NCOA3
Gene Accession No. Q9Y6Q9
Gene Alias 2010305B15Rik; Actr; AIB1; AIB-1; amplified in breast cancer 1 protein; amplified in breast cancer-1 protein homolog; AW321064; BHLHE42; CAGH16; CBP-interacting protein; class E basic helix-loop-helix protein 42; CTG26; KAT13B; MGC141848; NCOA3; NCoA-3; Nuclear receptor coactivator 3; OTTHUMP00000031716; p/Cip; pCip; Rac3; RAC-3; Receptor-associated coactivator 3; RP5-1049G16.3; Src3; SRC-3; steroid receptor coactivator protein 3; Thyroid hormone receptor activator molecule 1; TNRC14; TNRC16; Tram1; Tram-1
Gene Symbols NCOA3
Host Species Mouse
Immunogen GST fusion protein encoding amino acid residues 605-1294 of human AIB1.
Purification Method Purified
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8202
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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