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Invitrogen™ SRC3 Polyclonal Antibody
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Catalog No. PIPA529854
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100 μL
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PIPA529854 100 μL
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Catalog No. PIPA529854 Supplier Invitrogen™ Supplier No. PA529854
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: K562, A431, HeLa, HepG2. Predicted reactivity: Mouse (95%), Xenopus laevis (91%), Pig (85%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

AIB1-AC3 recognizes AIB1, a member of the SRC-1 family of nuclear receptor coactivators with an apparent molecular weight of 160kDa. The AIB1 gene has been mapped to region 20q12 and has been shown to be amplified in breast tumors and pancreatic cancer cell lines. AIB1 interacts in a ligand-dependent fashion with the estrogen receptor to enhance estrogen-dependent transcriptional gene activation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SRC3
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene NCOA3
Gene Accession No. Q9Y6Q9
Gene Alias 2010305B15Rik; Actr; AIB1; AIB-1; amplified in breast cancer 1 protein; amplified in breast cancer-1 protein homolog; AW321064; BHLHE42; CAGH16; CBP-interacting protein; class E basic helix-loop-helix protein 42; CTG26; KAT13B; MGC141848; NCOA3; NCoA-3; Nuclear receptor coactivator 3; OTTHUMP00000031716; p/Cip; pCip; Rac3; RAC-3; Receptor-associated coactivator 3; RP5-1049G16.3; Src3; SRC-3; steroid receptor coactivator protein 3; Thyroid hormone receptor activator molecule 1; TNRC14; TNRC16; Tram1; Tram-1
Gene Symbols NCOA3
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the N-terminus region of human SRC3. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8202
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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