Invitrogen™ SRC3 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA5142351

Catalog No. PIPA5142351

Description

Additional Information: This antibody is expected to recognise both reported isoforms (NP_006525.2; NP_858045.1). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.

AIB1-AC3 recognizes AIB1, a member of the SRC-1 family of nuclear receptor coactivators with an apparent molecular weight of 160kDa. The AIB1 gene has been mapped to region 20q12 and has been shown to be amplified in breast tumors and pancreatic cancer cell lines. AIB1 interacts in a ligand-dependent fashion with the estrogen receptor to enhance estrogen-dependent transcriptional gene activation.

Specifications

• Antigen: SRC3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NCOA3
• Gene Alias: 2010305B15Rik; Actr; AIB1; AIB-1; amplified in breast cancer 1 protein; amplified in breast cancer-1 protein homolog; AW321064; BHLHE42; CAGH16; CBP-interacting protein; class E basic helix-loop-helix protein 42; CTG26; KAT13B; MGC141848; NCOA3; NCoA-3; Nuclear receptor coactivator 3; OTTHUMP00000031716; p/Cip; pCip; Rac3; RAC-3; Receptor-associated coactivator 3; RP5-1049G16.3; Src3; SRC-3; steroid receptor coactivator protein 3; Thyroid hormone receptor activator molecule 1; TNRC14; TNRC16; Tram1; Tram-1
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 8202
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9Y6Q9
• Gene Symbols: NCOA3
• Immunogen: Peptide with sequence C-TNETQRQKSHT.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov