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SRp75 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501565740
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50-156-5740 100 μL
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Catalog No. 50-156-5740 Supplier Bethyl Laboratories, Inc Supplier No. A303671A
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Serine/arginine-rich protein 75 (SRp75) is encoded by the SRSF4 gene. SRp75 belongs to the arginine/serine-rich factor family and likely plays a role in alternative mRNA splicing.The family of SR factors all contain one or more RNA recognition motifs (RRM) and an arginine/ serine (RS)-rich domain. They are not only essential for constitutive splicing but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. The majority of SR proteins, including SC35 and SRp40, are confined to the nucleus, while SF2/ASF, SRp20, and 9G8 are continuously shuttled between the nucleus and the cytoplasm and contribute to mRNA transport. The activity of SR proteins in regulated splicing is antagonized by members of the hnRNP A/B family of proteins, which induce drastic shifts in the selection of splicing sites.

Specifications

Antigen SRp75
Applications Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene SRSF4
Gene Accession No. Q08170
Gene Alias arginine/serine-rich 4, Pre mRNA splicing factor SRP75, Pre-mRNA-splicing factor SRP75, Serine/arginine-rich splicing factor 4, Splicing factor, Splicing factor, arginine/serine rich 4, SRP001LB, SRP75, Srsf4
Gene Symbols SRSF4
Host Species Rabbit
Immunogen Between 400 and 450
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6429
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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