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SRPX2 Mouse anti-Human, Mouse, Porcine, Clone: 2A1D7, Proteintech
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Catalog No. 501736699 Shop All Proteintech Group Inc Products
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50-173-6699 150 μL
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Catalog No. 50-173-6699 Supplier Proteintech Group Inc Supplier No. 662661IG150UL
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Mouse Monoclonal Antibody

Sushi-repeat-containing protein X-linked 2 (SRPX2) is a neural gene functioning in the speech and language center of the human brain; mutations in this gene lead to epilepsy, speech dyspraxia, mental retardation and cognitive disorders. Recently, SRPX2 was found to be a novel mediator of angiogenesis and can act as a ligand for the urokinase-type plasminogen activator, a protein that can facilitate invasive migration of sprouting endothelial cells. SRPX2 is also overexpressed in gastric cancer, leading to increased phosphorylation levels of focal adhesion kinase and enhanced cellular migration and adhesion, suggesting that SRPX2 may be a potential target in the treatment of metastatic cancers.

Specifications

Antigen SRPX2
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 2A1D7
Concentration 1.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SRPX2
Gene Accession No. O60687, Q8R054
Gene Alias BPP, CBPS, PMGX, RESDX, SRPUL, SRPX2
Gene Symbols SRPX2
Host Species Mouse
Immunogen SRPX2 Fusion Protein Ag8084
Purification Method Protein A
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100153130, 27286, 68792
Target Species Human, Mouse, Pig
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG2b
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