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Invitrogen™ SRPX2 Polyclonal Antibody
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Catalog No. PIPA590463
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100 μL
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PIPA590463 100 μL
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Catalog No. PIPA590463 Supplier Invitrogen™ Supplier No. PA590463
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DGRWSGGEPV CVDIDPPKIR CPHSREKMAE PEKLTARVYW DPPLVKDSAD GTITRVTLRG PEPGSHFPEG EHVIRYTAYD RAYNRASCKF IVKVQVRRCP TLKPPQHGYL TCTSAGDNYG ATCEYHCDGG YDRQGTPSRV CQSSRQWSGS PPICAPMKIN VNVNSAAGLL DQFYEKQRLL IISAPDPSNR YYKMQISMLQ QSTCGLDLRH VTIIELVGQP PQEVGRIREQ QLSANIIEEL RQFQRLTRSY FNMVLIDKQG IDRDRYMEPV TPEEIFTFID DYLLSNQELT QRREQRDICE; Positive Samples: Mouse brain; Cellular Location: Cell junction, Cell surface, Cytoplasm, synapse.

Sushi-repeat-containing protein X-linked 2 (SRPX2) is a neural gene functioning in the speech and language center of the human brain; mutations in this gene lead to epilepsy, speech dyspraxia, mental retardation and cognitive disorders. Recently, SRPX2 was found to be a novel mediator of angiogenesis and can act as a ligand for the urokinase-type plasminogen activator, a protein that can facilitate invasive migration of sprouting endothelial cells. SRPX2 is also overexpressed in gastric cancer, leading to increased phosphorylation levels of focal adhesion kinase and enhanced cellular migration and adhesion, suggesting that SRPX2 may be a potential target in the treatment of metastatic cancers.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SRPX2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.35 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene SRPX2
Gene Accession No. Q8R054
Gene Alias 1110039C07Rik; BPP; CBPS; EMBL:AAI68975.1, ECO:0000312; PMGX; PubMed:24179158}; RESDX; RGD:1562444}; RGD1562444; RP11-524D16__A.1; SRP; SRPUL; SRPX2; srpx2 {ECO:0000312; sushi repeat containing protein X-linked 2; sushi repeat containing protein, X-linked 2; sushi repeat-containing protein SRPX2; sushi repeat-containing protein SRPX2 {ECO:0000303; sushi-repeat containing protein; sushi-repeat containing protein, X-linked 2; sushi-repeat protein; sushi-repeat protein upregulated in leukemia; sushi-repeat protein up-regulated in leukemia; sushi-repeat-containing protein, X-linked 2
Gene Symbols SRPX2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 166-465 of human SRPX2 (NP_0552821).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 68792
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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