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SRPX2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501981829
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50-198-1829 100 μL
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Catalog No. 50-198-1829 Supplier Bioss Supplier No. BS11967R
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Rabbit Polyclonal Antibody

Sushi-repeat-containing protein X-linked 2 (SRPX2) is a neural gene functioning in the speech and language center of the human brain; mutations in this gene lead to epilepsy, speech dyspraxia, mental retardation and cognitive disorders. Recently, SRPX2 was found to be a novel mediator of angiogenesis and can act as a ligand for the urokinase-type plasminogen activator, a protein that can facilitate invasive migration of sprouting endothelial cells. SRPX2 is also overexpressed in gastric cancer, leading to increased phosphorylation levels of focal adhesion kinase and enhanced cellular migration and adhesion, suggesting that SRPX2 may be a potential target in the treatment of metastatic cancers.

Specifications

Antigen SRPX2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene SRPX2
Gene Accession No. O60687
Gene Alias 1110039C07Rik; BPP; CBPS; EMBL:AAI68975.1, ECO:0000312; PMGX; PubMed:24179158}; RESDX; RGD:1562444}; RGD1562444; RP11-524D16__A.1; SRP; SRPUL; SRPX2; srpx2 {ECO:0000312; sushi repeat containing protein, X-linked 2; Sushi repeat-containing protein SRPX2; sushi repeat-containing protein SRPX2 {ECO:0000303; sushi-repeat containing protein; sushi-repeat containing protein, X-linked 2; Sushi-repeat protein upregulated in leukemia; sushi-repeat protein up-regulated in leukemia; sushi-repeat-containing protein, X-linked 2
Gene Symbols SRPX2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human SRPX2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27286
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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