Invitrogen™ SRRM1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA562100

Catalog No. PIPA562100

Description

Immunogen sequence: RQRTKSRSPS PAPEKKEKTP ELPEPSVKVK EPSVQEATST SDILKVPKPE PIPEPKEPSP E Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 87%.

Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates.

Specifications

• Antigen: SRRM1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SRRM1
• Gene Alias: 160-KD; AA407769; LOW QUALITY PROTEIN: serine/arginine repetitive matrix protein 1; plenty-of-prolines 101; plenty-of-prolines-101; Pop101; Ser/Arg-related nuclear matrix protein; serine and arginine repetitive matrix 1; serine/arginine repetitive matrix 1; serine/arginine repetitive matrix protein 1; Srm160; SR-related nuclear matrix protein of 160 kDa; SRRM1; wu:fb34f04; wu:fb38b06; zgc:63802
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10250
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8IYB3
• Gene Symbols: SRRM1
• Immunogen: Recombinant protein corresponding to Human SRRM1. Recombinant protein control fragment (Product #RP-100820).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov