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Invitrogen™ SRRM1 Polyclonal Antibody
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Catalog No. PIPA5114779
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100 μL
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PIPA5114779 100 μL
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Catalog No. PIPA5114779 Supplier Invitrogen™ Supplier No. PA5114779
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total SRRM1.

Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SRRM1
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene SRRM1
Gene Accession No. Q52KI8, Q8IYB3
Gene Alias 160-KD; AA407769; LOW QUALITY PROTEIN: serine/arginine repetitive matrix protein 1; plenty-of-prolines 101; plenty-of-prolines-101; Pop101; Ser/Arg-related nuclear matrix protein; serine and arginine repetitive matrix 1; serine/arginine repetitive matrix 1; serine/arginine repetitive matrix protein 1; Srm160; SR-related nuclear matrix protein of 160 kDa; SRRM1; wu:fb34f04; wu:fb38b06; zgc:63802
Gene Symbols SRRM1
Host Species Rabbit
Immunogen A synthesized peptide derived from human SRRM1(Accession Q8IYB3), corresponding to amino acid residues P847-K897.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10250, 51796
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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