Invitrogen™ SRSF11 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101910

Catalog No. PIPA5101910

Description

Antibody detects endogenous levels of total SFRS11.

Pre-mRNA splicing enhancer elements are short RNA sequences capable of activating weak splice sites in nearby introns that are required for accurate splice site recognition and the control of alternative splicing. Splicing enhancer elements contain specific binding sites for serine/arginine (SR)-rich splicing factors, which include SC35, 9G8, SRp20 and SF2/ASF. The family of SR factors all contain one or more RNA recognition motifs (RRM) and a SR-rich domain. The SR factor family is not only essential for constitutive splicing, but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. SFRS11 (splicing factor, arginine/serine-rich 11), also known as arginine-rich 54 kDa nuclear protein (p54) or NET2, is a 484 amino acid nuclear protein that colocalizes with spliceosome components and belongs to the splicing factor SR family. SFRS11 may function in pre-mRNA splicing and contains one RRM (RNA recognition motif) domain.

Specifications

• Antigen: SRSF11
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SRSF11
• Gene Alias: 0610009J05Rik; 2610019N13Rik; Arginine-rich 54 kDa nuclear protein; BF642805; dJ677H15.2; NET2; p54; serine and arginine rich splicing factor 11; serine/arginine-rich splicing factor 11; SFR11; Sfrs11; splicing factor p54; splicing factor, arginine/serine-rich 11; SR splicing factor 11; Srsf11
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 69207, 9295
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q05519
• Gene Symbols: SRSF11
• Immunogen: A synthesized peptide derived from human SRSF11(Accession Q05519), corresponding to amino acid residues E441-D484.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG