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Invitrogen™ SRSF4 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA562282
Description
Immunogen sequence: SVSKEREHAK SESSQREGRG ESENAGTNQE TRSR Highest antigen sequence identity to the following orthologs: Mouse - 65%, Rat - 62%.
Serine/arginine-rich protein 75 (SRp75) is encoded by the SRSF4 gene. SRp75 belongs to the arginine/serine-rich factor family and likely plays a role in alternative mRNA splicing.The family of SR factors all contain one or more RNA recognition motifs (RRM) and an arginine/ serine (RS)-rich domain. They are not only essential for constitutive splicing but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. The majority of SR proteins, including SC35 and SRp40, are confined to the nucleus, while SF2/ASF, SRp20, and 9G8 are continuously shuttled between the nucleus and the cytoplasm and contribute to mRNA transport. The activity of SR proteins in regulated splicing is antagonized by members of the hnRNP A/B family of proteins, which induce drastic shifts in the selection of splicing sites.
Specifications
SRSF4 | |
Polyclonal | |
Unconjugated | |
SRSF4 | |
5730499P16Rik; AW550192; MNCb-2616; Pre-mRNA-splicing factor SRP75; RGD1561347; serine and arginine rich splicing factor 4; serine/arginine-rich splicing factor 4; SFRS4; splicing factor, arginine/serine-rich 4; splicing factor, arginine/serine-rich 4 (SRp75); SR splicing factor 4; SRP001LB; SRP75; SRSF4 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
6429 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Immunocytochemistry | |
0.2 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
Q08170 | |
SRSF4 | |
Recombinant protein corresponding to Human SRSF4. Recombinant protein control fragment (Product #RP-101229). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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