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  5. Tocris Bioscience™ SRT 1720

Tocris Bioscience™ SRT 1720
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Catalog No. 755850
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75-585-0 50 mg
75-581-0 10 mg
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Catalog No. 75-585-0 Supplier Tocris Bioscience™ Supplier No. 7558/50
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Description

Selective SIRT1 activator; induces autophagy and mitochondrial biogenesis

SRT 1720 is selective SIRT 1 activator (EC50 = 0.16 μM). SRT 1720 inhibits growth of bladder cancer organoids and xenografts (IC50 = 0.35 μM) and induces autophagy. In vitro, SRT 1720 increases mitochondrial biogenesis and recovery after oxidation injury and reduces palmitate-induced insulin resistance. Also improves survival and healthspan of obese mice.

Specifications

Chemical Name or Material N-[2-[3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-quinoxalinecarboxamide
CAS 925434-55-5
Quantity 50 mg
Target Sirtuin 1/SIRT1
Molecular Formula C25H23N7OS
Purity 0.98
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