Invitrogen™ SRY Monoclonal Antibody (1G4)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA517181

Catalog No. PIMA517181

Description

MA5-17181 targets SRY in FACS, IHC, indirect ELISA, and WB applications and shows reactivity with Human samples. The MA5-17181 immunogen is purified recombinant fragment of human SRY (amino acids:1-204) expressed in E. Coli. MA5-17181 detects SRY which has a predicted molecular weight of approximately 23.9kDa.

This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome.

Specifications

• Antigen: SRY
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: Q05066
• Gene Symbols: SRY
• Immunogen: Purified recombinant fragment of human SRY (amino acids:1-204) expressed in E. Coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Clone: 1G4
• Conjugate: Unconjugated
• Gene: SRY
• Gene Alias: essential protein for sex determination in human males; HMG box transcription factor Sry1; HMG box transcription factor Sry3BI; sex determining region of Chr Y; sex determining region on Y; sex determining region Y; sex determining region Y protein; sex-determining region on Y; sex-determining region Y protein; SRXX1; SRXY1; Sry; Sry1; Sry3BI; SRYGENE; TDF; TDY; Testis determining locus; testis determining-Y; testis-determining factor; testis-determining factor on Y
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 6736
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid