Invitrogen™ SRY Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101147

Catalog No. PIPA5101147

Description

Antibody detects endogenous levels of total SRY.

This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome.

Specifications

• Antigen: SRY
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SRY
• Gene Alias: essential protein for sex determination in human males; HMG box transcription factor Sry1; HMG box transcription factor Sry3BI; sex determining region of Chr Y; sex determining region on Y; sex determining region Y; sex determining region Y protein; sex-determining region on Y; sex-determining region Y protein; SRXX1; SRXY1; Sry; Sry1; Sry3BI; SRYGENE; TDF; TDY; Testis determining locus; testis determining-Y; testis-determining factor; testis-determining factor on Y
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 25221, 6736
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P36394, Q05066
• Gene Symbols: SRY
• Immunogen: A synthesized peptide derived from human SRY(Accession Q05066), corresponding to amino acid residues V60-F110.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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