SS18 Mouse anti-Human, Clone: OTI4F11, lyophilized, TrueMAB™

Catalog No.	Quantity
50-166-9779	100 μg

Catalog No. 50-166-9779 Supplier OriGene Supplier No. CF809897

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The transcriptional coactivator SYT (synovial translocation protein) contains a conserved amino terminal SNH domain and a carboxy terminal QPGY domain, which is a functioning transcriptional activating sequence. Synovial sarcoma translocation (SSX) proteins, including SSX1-5, are transcriptional repressors that contain a repressor domain in their carboxy termini. SSX proteins are localized to the nucleus and expressed in testis and several types of cancers and, therefore, they are classified as C/T (cancer/testis) antigens. The t(x;18) translocation results in the fusion of the amino terminus of SYT to the carboxy terminus of either SSX1 or SSX2; both fusions result in the production of transcriptional activators.

Specifications

• Antigen: SS18
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI4F11
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: SS18
• Gene Accession No.: Q15532
• Gene Alias: SSXT, SYT
• Gene Symbols: SS18
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 227-255 of human SS18 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6760
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG1