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Invitrogen™ SS18 Polyclonal Antibody
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Catalog No. PA549678
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100 μL
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PA549678 100 μL
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Catalog No. PA549678 Supplier Invitrogen™ Supplier No. PA549678
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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous level of total SYT protein.

The transcriptional coactivator SYT (synovial translocation protein) contains a conserved amino terminal SNH domain and a carboxy terminal QPGY domain, which is a functioning transcriptional activating sequence. Synovial sarcoma translocation (SSX) proteins, including SSX1-5, are transcriptional repressors that contain a repressor domain in their carboxy termini. SSX proteins are localized to the nucleus and expressed in testis and several types of cancers and, therefore, they are classified as C/T (cancer/testis) antigens. The t(x;18) translocation results in the fusion of the amino terminus of SYT to the carboxy terminus of either SSX1 or SSX2; both fusions result in the production of transcriptional activators.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SS18
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene SS18
Gene Accession No. Q15532, Q62280
Gene Alias D130059H17; MGC116875; Protein SSXT; Protein SYT; SS18; SS18, nBAF chromatin remodeling complex subunit; Ssxt; synovial sarcoma associated SS18-beta; synovial sarcoma associated SS18-delta; synovial sarcoma associated SS18-gamma; synovial sarcoma translocated to X chromosome protein; synovial sarcoma translocation; synovial sarcoma translocation, chromosome 18; synovial sarcoma, translocated to X chromosome; synovial sarcoma-associated Ss18-alpha; SYT
Gene Symbols SS18
Host Species Rabbit
Immunogen Peptide sequence around aa.14~18(G-E-I-T-P) derived from Human SYT.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 268996, 361295, 6760
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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