Invitrogen™ SSB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120047

Catalog No. PIPA5120047

Description

Positive test controls include: Jurkat, LO2, HepG2, 293T. The target is usually found in the following locations: Nucleus. Immunogen sequence: KFVETPGQKY KETDLLILFK DDYFAKKNEE RKQNKVEAKL RAKQEQEAKQ KLEEDAEMKS LEEKIGCLLK FSGDLDDQTC REDLHILFSN HGEIKWIDFV RGAKEGIILF KEKAKEALGK AKDANNGNLQ LRNKEVTWEV LEGEVEKEAL KKIIEDQQES LNKWKSKGRR FKGKGKGNKA AQPGSGKGKV QFQGKKTKFA SDDEHDEHDE NGATGPVKRA REETDKEEPA SKQQKTENGA GDQ.

La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome and systemic lupus erythematosus.

Specifications

• Antigen: SSB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SSB
• Gene Alias: autoantigen La; La; la autoantigen; La autoantigen homolog; La protein; la ribonucleoprotein; La ribonucleoprotein domain family, member 3; La/SSB; LARP3; lupus La antigen; lupus La protein; Lupus La protein homolog; Lupus LA protein homolog (LA ribonucleoprotein) (LA autoantigen homolog); lupus La protein-like; mRNA for autoantigen; OTTHUMP00000204777; sjoegren syndrome type B antigen; Sjogren syndrome antigen B; Sjogren syndrome antigen B (autoantigen La); small RNA binding exonuclease protection factor La; Ssb; SS-B; SS-B/La protein
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6741
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 4.89 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P05455
• Gene Symbols: SSB
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 166-408 of human SSB (NP_003133.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG