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Invitrogen™ SSEA1 Monoclonal Antibody (4E10)
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Catalog No. PIMA517042
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100 μL
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PIMA517042 100 μL
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Catalog No. PIMA517042 Supplier Invitrogen™ Supplier No. MA517042
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Description

Mouse Monoclonal Antibody

MA5-17042 targets CD15 in indirect ELISA, ICC, IHC, and IF applications and shows reactivity with Human samples. The MA5-17042 immunogen is synthesized peptide of human CD15. MA5-17042 detects CD15 which has a predicted molecular weight of approximately 59kDa.

CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin's disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SSEA1
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Monoclonal
Clone 4E10
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.03% sodium azide
Gene FUT4
Gene Accession No. P22083
Gene Alias FUTIV; Lewis X; SSEA-1
Gene Symbols FUT4
Host Species Mouse
Immunogen Synthesized peptide of human CD15.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2526
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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