Invitrogen™ SSEA3 Monoclonal Antibody (MC-631)

Rat Monoclonal Antibody

Supplier:  Invitrogen™ MA1020

Catalog No. PIMA1020

Description

SSEA3 Monoclonal Antibody for ICC/IF, Flow

SSEA-3 (stage-specific embryonic antigen 3) is a cell surface antigen, expressed along with SSEA-4, TRA-1-60 and TRA-1-81 in embryonic stem cells, embryonal carcinoma cells, and induced pluripotent stem cells (iPS). In human cells, these surface markers are down-regulated during the differentiation process, while SSEA1 is absent in undifferentiated human stem cells and upregulated on the cell surface after retinoic acid mediated differentiation. Conversely, in mouse stem cells, SSEA-1 expression decreases with differentiation while SSEA-3 and SSEA-4 expression increase.

Specifications

• Antigen: SSEA3
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: Potassium Phosphate with 1 mg/mL BSA, 0.15M NaCl and 0.05% sodium azide
• Host Species: Rat
• Purification Method: Affinity chromatography - MBP
• Regulatory Status: RUO
• Target Species: Human
• Product Type: Antibody
• Isotype: IgM

• Applications: Flow Cytometry, Immunocytochemistry
• Clone: MC-631
• Conjugate: Unconjugated
• Gene Alias: SSEA-3; stage-specific embryonic antigen 3
• Immunogen: Fischer rat immunized with 4-8 cell stage mouse embryos.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid