Invitrogen™ SSH1 Monoclonal Antibody (6C11G9)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA531909

Catalog No. PIMA531909

Description

MA5-31909 has been tested in indirect ELISA.

This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: SSH1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: Q8WYL5
• Gene Symbols: SSH1
• Immunogen: Synthesized peptide fragment of human SLINGSHOT-1L (AA: 1032-1044 ) expressed in E. coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin)
• Clone: 6C11G9
• Conjugate: Unconjugated
• Gene: SSH1
• Gene Alias: hSSH-1L; KIAA1298; Protein phosphatase Slingshot homolog 1; slingshot homolog 1; slingshot protein phosphatase 1; SSH1; SSH1L; SSH-1L; SSH-like protein 1
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 54434
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid