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Invitrogen™ SSH1 Polyclonal Antibody
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Catalog No. PIPA5115922
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100 μL
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PIPA5115922 100 μL
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Catalog No. PIPA5115922 Supplier Invitrogen™ Supplier No. PA5115922
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Slingshot homolog 1.

This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SSH1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene SSH1
Gene Accession No. Q8WYL5
Gene Alias hSSH-1L; KIAA1298; Protein phosphatase Slingshot homolog 1; slingshot homolog 1; slingshot protein phosphatase 1; SSH1; SSH1L; SSH-1L; SSH-like protein 1
Gene Symbols SSH1
Host Species Rabbit
Immunogen A synthesized peptide derived from human SSH1(Accession Q8WYL5), corresponding to amino acid residues S1013-S1049.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54434
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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