Invitrogen™ SSH1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5115922

Catalog No. PIPA5115922

Description

Antibody detects endogenous levels of total Slingshot homolog 1.

This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: SSH1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SSH1
• Gene Alias: hSSH-1L; KIAA1298; Protein phosphatase Slingshot homolog 1; slingshot homolog 1; slingshot protein phosphatase 1; SSH1; SSH1L; SSH-1L; SSH-like protein 1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54434
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q8WYL5
• Gene Symbols: SSH1
• Immunogen: A synthesized peptide derived from human SSH1(Accession Q8WYL5), corresponding to amino acid residues S1013-S1049.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG