Invitrogen™ ssPA Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA580252

Catalog No. PIPA580252

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for E. coli ssPA/Stringent starvation protein A.

sspA preferentially cleaves peptide bonds on the carboxyl-terminal side of aspartate and glutamate. Along with other extracellular proteases it is involved in colonization and infection of human tissues. Required for proteolytic maturation of thiol protease SspB and inactivation of SspC, an inhibitor of SspB. It is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A, which are involved in adherence to host cells. May also protect bacteria against host defense mechanism by cleaving the immunoglobulin classes IgG, IgA and IgM. May be involved in the stability of secreted lipases.

Specifications

• Antigen: ssPA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Alias: Glutamyl endopeptidase; V8 protease; V8 proteinase
• Immunogen: Recombinant E. coli ssPA/Stringent starvation protein A protein.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Target Species: Bacteria
• Product Type: Antibody
• Isotype: IgG