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SSR 69071, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
10mg
This item is not returnable. View return policy
344930-95-6
C27H32N4O7S
556.634
DRZXDZYWZSKFDL-UHFFFAOYSA-N
d0b3mv,dsstox_cid_27368,dsstox_rid_82301,dsstox_gsid_47368,2-6-methoxy-4-1-methylethyl-1,1-dioxido-3-oxo-1,2-benzisothiazol-2 3h-yl methoxy-9-2-1-piperidinyl ethoxy-4h-pyrido 1,2-a pyrimidin-4-one,2-6-methoxy-1,1-dioxido-3-oxo-4-propan-2-yl-1,2-benzothiazol-2 3h-yl methoxy-9-2-piperidin-1-yl ethoxy-4h-py...
9872438
6-methoxy-1,1-dioxo-2-[[4-oxo-9-(2-piperidin-1-ylethoxy)pyrido[1,2-a]pyrimidin-2-yl]oxymethyl]-4-propan-2-yl-1,2-benzothiazol-3-one
CC(C)C1=CC(=CC2=C1C(=O)N(S2(=O)=O)COC3=CC(=O)N4C=CC=C(C4=N3)OCCN5CCCCC5)OC
This item is not returnable. View return policy
344930-95-6
C27H32N4O7S
556.634
DRZXDZYWZSKFDL-UHFFFAOYSA-N
d0b3mv,dsstox_cid_27368,dsstox_rid_82301,dsstox_gsid_47368,2-6-methoxy-4-1-methylethyl-1,1-dioxido-3-oxo-1,2-benzisothiazol-2 3h-yl methoxy-9-2-1-piperidinyl ethoxy-4h-pyrido 1,2-a pyrimidin-4-one,2-6-methoxy-1,1-dioxido-3-oxo-4-propan-2-yl-1,2-benzothiazol-2 3h-yl methoxy-9-2-piperidin-1-yl ethoxy-4h-py...
9872438
6-methoxy-1,1-dioxo-2-[[4-oxo-9-(2-piperidin-1-ylethoxy)pyrido[1,2-a]pyrimidin-2-yl]oxymethyl]-4-propan-2-yl-1,2-benzothiazol-3-one
CC(C)C1=CC(=CC2=C1C(=O)N(S2(=O)=O)COC3=CC(=O)N4C=CC=C(C4=N3)OCCN5CCCCC5)OC

Potent, orally active human leukocyte elastase inhibitor

High affinity, potent inhibitor of human leukocyte elastase (HLE) (IC 50 = 3.9 nM). Displays species-selectivity (K i values are 0.017, 1.70, 3.01, 58 and > 100 nM for human, mouse, rat, rabbit and porcine elastase respectively). Inhibits HLE-induced lung hemorrhage in mice (ID 50 = 2.8 mg/kg) and reduces infarct size in an in vivo acute model of coronary ischemia-reperfusion injury. Orally active.

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Quantity 10mg
Formula Weight 556.63
Percent Purity >98%
Chemical Name or Material SSR 69071

Recommended Storage : Store at +4°C