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SSR 69071, Tocris Bioscience™
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Quantity:
10 mg
Description
High affinity, potent inhibitor of human leukocyte elastase (HLE) (IC50 = 3.9 nM). Displays species-selectivity (Ki values are 0.017, 1.70, 3.01, 58 and > 100 nM for human, mouse, rat, rabbit and porcine elastase respectively). Inhibits HLE-induced lung hemorrhage in mice (ID50 = 2.8 mg/kg) and reduces infarct size in an in vivo acute model of coronary ischemia-reperfusion injury. Orally active.
Specifications
Specifications
Quantity | 10 mg |
Formula Weight | 556.63 |
Percent Purity | >98% |
Chemical Name or Material | SSR 69071 |
Safety and Handling
Recommended Storage | Store at +4°C |
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