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Tocris Bioscience™ SSR 69071
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Catalog No. 250610
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25-061-0 10 mg
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Description

Potent, orally active human leukocyte elastase inhibitor

High affinity, potent inhibitor of human leukocyte elastase (HLE) (IC50 = 3.9 nM). Displays species-selectivity (Ki values are 0.017, 1.70, 3.01, 58 and > 100 nM for human, mouse, rat, rabbit and porcine elastase respectively). Inhibits HLE-induced lung hemorrhage in mice (ID50 = 2.8 mg/kg) and reduces infarct size in an in vivo acute model of coronary ischemia-reperfusion injury. Orally active.

Chemical Identifiers

CAS 344930-95-6
Molecular Formula C27H32N4O7S

Specifications

Quantity 10 mg
Formula Weight 556.63
Purity >98%
Molecular Weight (g/mol) 556.634
Chemical Name or Material SSR 69071

Safety and Handling

Recommended Storage Store at +4°C
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