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Invitrogen™ SSTR3 Monoclonal Antibody (7H8E5)
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Catalog No. PIMA531915
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100 μL
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Catalog No. Quantity
PIMA531915 100 μL
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Catalog No. PIMA531915 Supplier Invitrogen™ Supplier No. MA531915
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Description

Mouse Monoclonal Antibody

MA5-31915 has been tested in indirect ELISA.

Expression of Somatostatin Receptor Type 3 (SSTR3) has been reported in brain, breast, eye, gastrointestinal tract, pancreas, and thyroid. G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist. All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms. An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors. Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs. This turn-off activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates. Two blockbuster drugs which have been developed as GPCR-targeted pharmaceuticals are Zyprexa (Eli Lilly) and Claritin (Schering-Plough) which have multi-billion dollar shares of the mental health and allergy markets, respectively.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SSTR3
Applications ELISA, Flow Cytometry, Western Blot
Classification Monoclonal
Clone 7H8E5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene Sstr3
Gene Accession No. P30936, P32745
Gene Alias Smstr28; Smstr3; Smstr-3; somatostatin receptor; somatostatin receptor 28; somatostatin receptor 3; somatostatin receptor subtype 3; somatostatin receptor type 3; SS3R; SS-3-R; SS3-R; SSR-28; sst3; SSTR; SSTR3
Gene Symbols Sstr3
Host Species Mouse
Immunogen Purified recombinant fragment of human SSTR3 (AA: 1-43) expressed in E. coli.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 171044, 6753
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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