Invitrogen™ SSTR5 Polyclonal Antibody

Catalog No.	Quantity
PIPA534224	50 μg

Catalog No. PIPA534224 Supplier Invitrogen™ Supplier No. PA534224

Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human (100%) Gorilla, Marmoset (94%).

Somatostatin is a multifunctional protein affecting exocrine and endocrine protein secretion, neurotransmission, and neuronal modulation and regulating cell proliferation. All these functions of Somatostatin are executed through a class of GPCR protein family members called somatostatin receptor. Till date, 6 classes of somatostatin receptors have been discovered out of which SSTR5, 364A.A protein, is a receptor subtype expressed predominantly in the pituitary and hypothalamus region of brain. Studies revealed that SSTR5 contains seven transmembrane regions and undergoes homodimerization and also heterodimerizes with SSTR1. Although the specific functions of SSTR5 are still elusive, the studies indicate that it complements SSTR2 regulation of ACTH secretion. Polymorphisms in SSTR5 gene have been observed in patients with acromegaly.

Specifications

• Antigen: SSTR5
• Applications: Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.1% sodium azide
• Gene: Sstr5
• Gene Accession No.: P35346
• Gene Alias: Smstr5; Somato; somatostatin receptor; somatostatin receptor 5; Somatostatin receptor subtype 5; somatostatin receptor type 5; SS5R; SS-5-R; SS5-R; sst5; Sstr5
• Gene Symbols: Sstr5
• Host Species: Rabbit
• Immunogen: Synthetic 18 amino acid peptide from C-terminus of human SSTR5.
• Purification Method: Antigen Affinity Chromatography
• Quantity: 50 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6755
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG