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Invitrogen™ SSX2 Polyclonal Antibody
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Catalog No. PIPA561070
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100 μL
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PIPA561070 100 μL
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Catalog No. PIPA561070 Supplier Invitrogen™ Supplier No. PA561070
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GKHAWTHRLR ERKQLVIYEE ISDPEEDDE Highest antigen sequence identity to the following orthologs: Mouse - 66%, Rat - 79%.

SSX2 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SSX2
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Ssx2
Gene Accession No. Q16385
Gene Alias cancer/testis antigen 5.2; cancer/testis antigen family 5, member 2a; CT5.2; CT5.2A; CT52; HD21; HOM-MEL-40; LOC103690782; MGC119055; MGC15364; MGC3884; Protein SSX2; putative protein SSX10; sarcoma, synovial, X-chromosome-related 2; SSX; SSX family member 2; SSX2; SSX2A; SSX2B; Synovial sarcoma, X breakpoint 2; synovial sarcoma, X breakpoint 2B; tumor antigen HOM-MEL-40
Gene Symbols Ssx2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SSX1.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6757
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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