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Invitrogen™ SSX4 Polyclonal Antibody
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Catalog No. PIPA596866
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100 μL
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PIPA596866 100 μL
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Catalog No. PIPA596866 Supplier Invitrogen™ Supplier No. PA596866
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: FMRSKRAADF HGNDFGNDRN HRNQVERPQM TFGSLQRIFP KIMPKKPAEE ENGLKEVPEA SGPQNDGKQL CPPGNPSTLE KINKTSGPKR GKHAWTHRLR ERKQLVVYEE ISDPEEDDE; Positive Samples: Mouse kidney, Mouse lung.

SSX4 belongs to the SSX family. It contains 1 KRAB-related domain. SSX4 could act as a modulator of transcription. The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4, represents the more telomeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SSX4
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.45 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene SSX4
Gene Accession No. O60224
Gene Alias cancer/testis antigen 5.4; CT5.4; MGC119056; MGC12411; Protein SSX4; SSX family member 4; SSX4; SSX4A; SSX4B; synovial sarcoma, X breakpoint 4
Gene Symbols SSX4
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 70-188 of human SSX4 (NP_0056271).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6759
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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