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Tocris Bioscience™ ST 045849
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Catalog No. 677510
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67-751-0 10 mg
67-755-0 50 mg
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Description

O-GlcNAc transferase (OGT) inhibitor

ST 045849 is an O-GlcNAc transferase (OGT) inhibitor (IC50 = 53 μM). Reduces proliferation and viability of prostate cancer cells in vitro. Depletes intracellular alanine and decreases glucose consumption by cancer cells. Decreases markers of ER stress and apoptosis in pregnant diabetic mice and reduces neural tube defects in embryos from diabetic mice.

Specifications

Chemical Name or Material 2-[(4-Chlorophenyl)imino]tetrahydro-4-oxo-3-(2-tricyclo[3.3.1.13,7]dec-1-ylethyl)-2H-1,3-thiazine-6-carboxylic acid
CAS 442665-87-4
Quantity 10 mg
Molecular Formula C23H27ClN2O3S
Purity 98%
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