Invitrogen™ ST3GAL5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530289

Catalog No. PIPA530289

Description

Recommended positive controls: A431, Jurkat, Raji, mouse brain, U87-MG. Predicted reactivity: Mouse (91%), Rat (90%), Sheep (95%), Rhesus Monkey (98%), Chimpanzee (98%), Bovine (94%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in this gene has been associated with Amish infantile epilepsy syndrome. Transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: ST3GAL5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ST3GAL5
• Gene Alias: [a]2; 3S-T; alpha 2,3-sialyltransferase V; alpha2,3-sialyltransferase; CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; Ganglioside GM3 synthase; GM3 synthase; GM3S; GM3-specific sialytransferase; lactosylceramide alpha-2,3-sialyltransferase; lactosylceramide alpha-2,3-sialyltransferas-like protein; mST3Gal V; SATI; Sialyltransferase 9; sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase); sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; GM3 synthase); Siat9; SIATGM3S; ST3 beta-galactoside alpha-2,3-sialyltransferase 5; ST3 beta-galactoside alpha-23-sialyltransferase 5; ST3Gal V; ST3GAL5; ST3GalV; ST3GAL-V; UNQ2510/PRO5998
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20454, 8869
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O88829, Q9UNP4
• Gene Symbols: ST3GAL5
• Immunogen: Recombinant fragment corresponding to a region within amino acids 174 and 418 of Human ST3GAL5.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG