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Invitrogen™ ST3GAL6 Polyclonal Antibody
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Catalog No. PIPA520748
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100 μg
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Catalog No. Quantity
PIPA520748 100 μg
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Catalog No. PIPA520748 Supplier Invitrogen™ Supplier No. PA520748
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Description

Rabbit Polyclonal Antibody

A suggested positive control is Hela cell lysate. PA5-20748 can be used with blocking peptide PEP-0862.

Sialyltransferases catalyze the transfer of sialic acid from cytidine 5-prime monophospho-N-acetylneuraminic acid (CMP-NeuAc) to terminal positions of glycoprotein and glycolipid carbohydrate groups. Terminal NeuAc residues are key determinants of carbohydrate structures, such as the sialyl-Lewis X determinants, and are widely distributed in many cell types. However, cancer cells often express more heavily sialylated glycans on their cell surface and this feature sometimes correlates with invasiveness. In contrast, expression of ST3gal6, a member of the sialyltransferase family that sialylates type II lactosamine structures on glycoproteins and glycolipids, was found to be significantly decreased by hypermethylation of the gene in gastrointestinal cancer. At least three isoforms of ST3gal6 are known to exist.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ST3GAL6
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene ST3GAL6
Gene Accession No. P61943, Q8VIB3, Q9Y274
Gene Alias 1700023B24Rik; AI930218; alpha2,3-sialyltransferase ST3Gal VI; alpha-2,3-sialyltransferase VI; AW552396; CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI; sia10; Sialyltransferase 10; sialyltransferase 10 (alpha-2,3-sialyltransferase VI); SIAT10; ST3 beta-galactoside alpha-2,3-sialyltransferase 6; ST3Gal VI; ST3GAL6; ST3GalVI; type 2 lactosamine alpha-2,3-sialyltransferase
Gene Symbols ST3GAL6
Host Species Rabbit
Immunogen A 16 amino acid peptide from near the carboxy terminus of human ST3gal6.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10402, 304023, 54613
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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