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Invitrogen™ ST5 Polyclonal Antibody
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Catalog No. PIPA5101138
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100 μL
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PIPA5101138 100 μL
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Catalog No. PIPA5101138 Supplier Invitrogen™ Supplier No. PA5101138
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ST5.

This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ST5
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene DENND2B
Gene Accession No. P78524, Q924W7
Gene Alias 2010004M01Rik; 2610305K15Rik; DENN domain-containing protein 2B; DENN/MADD domain containing 2B; DENND2B; HeLa tumor suppression 1; HTS1; p126; p70; St5; suppression of tumorigenicity 5; suppression of tumorigenicity 5 protein
Gene Symbols DENND2B
Host Species Rabbit
Immunogen A synthesized peptide derived from human ST5(Accession P78524), corresponding to amino acid residues A417-T467.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6764, 76954
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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