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ST5 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501987056
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50-198-7056 100 μL
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Catalog No. 50-198-7056 Supplier Bioss Supplier No. BS6112R
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Rabbit Polyclonal Antibody

This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.

Specifications

Antigen ST5
Applications Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene DENND2B
Gene Accession No. P78524
Gene Alias 2010004M01Rik; 2610305K15Rik; DENN domain-containing protein 2B; DENN/MADD domain containing 2B; Dennd2b; HeLa tumor suppression 1; HTS1; p126; p70; St5; suppression of tumorigenicity 5; Suppression of tumorigenicity 5 protein
Gene Symbols DENND2B
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human ST5/DENND2B.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6764
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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