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Invitrogen™ Stabilin 2 Polyclonal Antibody
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Catalog No. PIPA555447
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100 μL
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PIPA555447 100 μL
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Catalog No. PIPA555447 Supplier Invitrogen™ Supplier No. PA555447
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VVLEEKLLKN DLHNGMHRET MLGFSYFLSF FLHNDQLYVN EAPINYTNVA TDKGVIHGLG KVLEIQKNRC DNNDTTIIRG RCRTCSSELT CPFGTKSLGN EKRRCIYTSY FMGRRTLFIG CQPKCVRTVI TR Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 79%.

This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Stabilin 2
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.20 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene STAB2
Gene Accession No. Q8WWQ8
Gene Alias 190 kDa form stabilin-2; 190 kDa hyaluronan receptor for endocytosis; CD44-like precursor FELL; DKFZP434E0321; FAS1 EGF-like and X-link domain containing adhesion molecule-2; FAS1 EGF-like and X-link domain-containing adhesion molecule 2; fasciclin egf-like, laminin-type egf-like, and link domain-containing scavenger receptor-2; fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2; FEEL2; FEEL-2; FELE-2; FELL; FELL2; FELL-2; FEX2; Hare; HAREFELL2; hepatic hyaluronan clearance receptor; hyaluronan receptor for endocytosis; hyaluronic acid receptor for endocytosis; MFEEL-2; SCARH1; scavenger receptor FEEL-2; Short form stabilin-2; stab2; STAB-2; stab2 {ECO:0000250; stabilin 2; Stabilin2; stabilin-2; UniProtKB:Q8WWQ8}
Gene Symbols STAB2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human Stabilin 2. Recombinant protein control fragment (Product #RP-90240).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55576
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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