Invitrogen™ STAM2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5121061

Catalog No. PIPA5121061

Description

Positive test controls include: MCF7, HepG2, OVCAR3, PC-3. The target is usually found in the following locations: Cytoplasm, Cytoplasmic side, Early endosome membrane, Peripheral membrane protein. Immunogen sequence: KLHPPAHYPP ASSGVPMQTY PVQSHGGNYM GQSIHQVTVA QSYSLGPDQI GPLRSLPPNV NSSVTAQPAQ TSYLSTGQDT VSNPTYMNQN SNLQSATGTT AYTQQMGMSV DMSSYQNTTS NLPQLAGFPV TVPAHPVAQQ HTNYHQQPLL.

The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation.

Specifications

• Antigen: STAM2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: STAM2
• Gene Alias: 1200004O12Rik; 5730456G07Rik; BB145015; DKFZp564C047; Hbp; HGNC:11358; Hrs binding protein; hrs-binding protein; HSE1 homolog; signal transducing adapter molecule 2; signal transducing adaptor molecule (SH3 domain and ITAM motif) 2; signal transducing adaptor molecule 2; STAM2; STAM-2; STAM2A; STAM2B; STAM-like protein containing SH3 and ITAM domains 2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10254, 311030, 56324
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.27 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O75886, O88811, Q5XHY7
• Gene Symbols: STAM2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 376-525 of human STAM2 (NP_005834.4).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG