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Invitrogen™ Staphylococcus aureus neutral proteinase Polyclonal Antibody
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Catalog No. FEPA5144507
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100 μL
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FEPA5144507 100 μL
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Catalog No. FEPA5144507 Supplier Invitrogen™ Supplier No. PA5144507
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Description

Rabbit Polyclonal Antibody

Staphylococcus aureus neutral proteinase Polyclonal Antibody for Western Blot, ELISA

Plays an essential role in immune evasion by helping bacteria to resist complement-mediated killing by neutrophils. Inhibits the deposition of host C3b on bacterial surfaces and the release of the chemoattractant C5a by cleaving the central complement protein C3. The cleavage site renders the C3b molecule vulnerable to proteolytic degradation by host regulators (PubMed:21502375). Cleaves and inactivates host SERPINA1, which is an endogenous protease inhibitor essential for controlling neutrophil serine protease elastase (PubMed:3533918). Also plays an essential role in the cleavage and subsequent activation of the serine protease SspA (glutamyl endopeptidase) which is involved in colonization and infection of human tissues (PubMed:17878159).
TRUSTED_SUSTAINABILITY

Specifications

Antigen Staphylococcus aureus neutral proteinase
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 4.18 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4
Gene Alias aur; Zinc metalloproteinase aureolysin
Host Species Rabbit
Immunogen Recombinant Staphylococcus aureus Zinc metalloproteinase aureolysin (aur) (210-509AA).
Purification Method Protein A/G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Bacteria
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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