STAR Rabbit anti-Human, Mouse, Porcine, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-7810	Proteintech Group Inc 122251AP150UL	150 μL

Description

Steroidogenic acute regulatory protein (StAR) plays a significant role in cholesterol transport from the cytoplasmic outer membrane to the inner mitochondrial membrane. The 37 kDa precursor is cleaved to generate an active 28 kDa protein capable of facilitating cholesterol metabolism into pregnenolone. StAR is prevalently expressed in mitochondria of steroid-producing adrenal and gonadal tissue. Abnormalities in StAR gene expression are impacted in autosomal Lipoid Congenial Adrenal Hyperplasia (LCAH) resulting in defects in pregnenolone and cortisol synthesis. The mechanism of cholesterol binding to StAR has yet to be elucidated.

Specifications

• Antigen: STAR
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Pig, Rat
• Gene Accession No.: P49675, P51557, P97826, Q28996
• Gene ID (Entrez): 20845, 25557, 396597, 6770
• Immunogen: STAR Fusion Protein Ag2862
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: STAR

• Concentration: 0.34 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: STAR, STARD1
• Gene Symbols: STAR
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody