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StAR Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501985500
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100 μL
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Catalog No. Quantity
50-198-5500 100 μL
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Catalog No. 50-198-5500 Supplier Bioss Supplier No. BS3570R
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Description

Rabbit Polyclonal Antibody

Steroidogenic acute regulatory protein (StAR) plays a significant role in cholesterol transport from the cytoplasmic outer membrane to the inner mitochondrial membrane. The 37 kDa precursor is cleaved to generate an active 28 kDa protein capable of facilitating cholesterol metabolism into pregnenolone. StAR is prevalently expressed in mitochondria of steroid-producing adrenal and gonadal tissue. Abnormalities in StAR gene expression are impacted in autosomal Lipoid Congenial Adrenal Hyperplasia (LCAH) resulting in defects in pregnenolone and cortisol synthesis. The mechanism of cholesterol binding to StAR has yet to be elucidated.

Specifications

Antigen StAR
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene STAR
Gene Accession No. P49675
Gene Alias AV363654; cholesterol trafficker; D8Ertd419e; lipid transporter; Luteinizing hormone-induced protein; mitochondrial steroid acute regulatory protein; Star; StAR related lipid transfer (START) domain containing 1; STARD1; StAR-related lipid transfer (START) domain containing 1; START domain containing 1; START domain-containing protein 1; steroid acute regulatory protein; steroidogenic acute regulator; steroidogenic acute regulatory protein; Steroidogenic acute regulatory protein, mitochondrial; testis secretory sperm-binding protein Li 241mP
Gene Symbols STAR
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human StAR.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6770
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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